Evaluation of the Antioxidant Capacity of Synthesized Coumarins

International Journal of Molecular Sciences

关键词: antioxidant capacity;    peroxyl radicals;    coumarins;    DPPH;    cyclic voltammetry;   

DOI  :  10.3390/ijms13067260

来源: DOAJ

【 摘 要 】

Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH^•) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.

【 授权许可】

Unknown