Current Approaches to PANS/PANDAS Diagnostics and Management

Voprosy Sovremennoj Pediatrii

Inna A. Kostik¹  Mikhail M. Kostik² 

[1] Children's Sanatorium-Rehabilitation Centre Detskye Duny;St. Petersburg State Pediatric Medical University;

关键词: children;    pandas;    pans;    cans;    pitand;    obsessive-compulsive syndrome;    tic;    hyperkinesis;    streptococcus;    etiology;    diagnostics;    management;   

DOI  :  10.15690/vsp.v18i5.2055

来源: DOAJ

【 摘 要 】

PANS, or Pediatric Acute-onset Neuropsychiatric Syndrome, is characterized by the sudden onset of obsessive-compulsive syndrome and accompanied by anxiety, emotional lability and other symptoms. PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections, is a subtype of PANS. Modern data on PANS/PANDAS etiology, pathogenesis, diagnostics and management is presented in this article. Therapeutic decisions on using anti-inflammatory and immunotropic therapy including non-steroidal anti-inflammatory drugs, glucocorticoids, intravenous immunoglobulin, plasmapheresis, rituximab and mycophenolate mofetil are analysed.

【 授权许可】

Unknown