Simulation of in vitro digestion coupled to gastric and intestinal transport models to estimate absorption of anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits

Journal of Functional Foods

Iva Fernandes¹  Renata Galhardo Borguini²  Isabel M.P.L.V.O. Ferreira²  Nuno Mateus²  Ana Cristina M.S. Gouvêa³  Ronoel L.O. Godoy³  Victor Freitas³  Fernanda Marques Peixoto⁴  Manuela C.P.A. Santiago⁴ 

[1] Fundação Centro Universitário Estadual da Zona Oeste, (UEZO) – Unidade de Farmácia, Av. Manuel Caldeira de Alvarenga, 1203 – Campo Grande, 23070-200, Rio de Janeiro, RJ, Brazil;Embrapa Agroindústria de Alimentos, Laboratório de Cromatografia Líquida, Avenida das Américas 29501, 23020-470, Guaratiba, Rio de Janeiro, RJ, Brazil;LAQV/REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal;Universidade Federal Rural do Rio de Janeiro (UFRRJ) – Programa em Pós-Graduação em Ciência e Tecnologia de Alimentos, Rodovia BR 465 – km 7, Campus Universitário – Seropédica, 23851-970 Rio de Janeiro, RJ, Brazil;

关键词: Bioaccessibility;    MKN-28;    Caco-2;    Myrciaria jabuticaba;    Syzygium malaccense;    Syzygium cumini;   

DOI  :  

来源: DOAJ

【 摘 要 】

The bioaccessibility of the anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits under gastro-intestinal conditions and their gastric and intestinal absorption was examined in order to estimate anthocyanin transport efficiency (ATE). Thus, in vitro digestion coupled to epithelium absorptive models (gastric MKN-28 and intestinal Caco-2) was applied independently for each phase. The bioaccessibility of anthocyanins after gastric digestion were 13% for jabuticaba, 45% for jambo and 65% for jamelão, whereas intestinal bioaccessibility were 10% for jabuticaba, 15% for jambo and 45% for jamelão. The assays showed that, applying the MKN-28 cell model, the ATE were 19.7, 9.7 and 14.1%, respectively, for jambo, jabuticaba, and jamelão powders, whereas using the Caco-2 cell model these results were 0.8, 0.2 and 0.3%, respectively. In conclusion gastric mucosa plays an important role in anthocyanin's absorption.

【 授权许可】

Unknown