Between‐study differences in grip strength: a comparison of Norwegian and Russian adults aged 40–69 years

Journal of Cachexia, Sarcopenia and Muscle

Jonas Johansson¹  Laila Arnesdatter Hopstock¹  Rachel Cooper²  Sarah Cook³  Vladimir M. Shkolnikov⁴  David A. Leon⁴  Alexander V. Kudryavtsev⁵  Bjørn Heine Strand⁶  Sofia Malyutina⁷  Andrew Ryabikov⁷ 

[1] Department of Community Medicine UiT The Arctic University of Norway Tromsø Norway;Department of Sport and Exercise Sciences, Musculoskeletal Science and Sports Medicine Research Centre Manchester Metropolitan University Manchester UK;Faculty of Epidemiology and Population Health London School of Hygiene & Tropical Medicine London UK;International Laboratory for Population and Health National Research University Higher School of Economics Moscow Russia;Northern State Medical University Arkhangelsk Russian Federation;Norwegian Institute of Public Health Oslo Norway;Research Institute of Internal and Preventive Medicine, Branch of Institute of Cytology and Genetics Siberian Branch of Russian Academy of Sciences Novosibirsk Russia;

关键词: Grip strength;    Sarcopenia;    Between‐country differences;    Lifestyle;    Body size;   

DOI  :  10.1002/jcsm.12816

来源: DOAJ

【 摘 要 】

Abstract Background Identifying individuals with low grip strength is an initial step in many operational definitions of sarcopenia. As evidence indicates that contemporaneous Russian populations may have lower mean levels of grip strength than other populations in northern Europe, we aimed to: compare grip strength in Russian and Norwegian populations by age and sex; investigate whether height, body mass index, education, smoking status, alcohol use and health status explain observed differences and; examine implications for case‐finding low muscle strength. Methods We used harmonized cross‐sectional data on grip strength and covariates for participants aged 40–69 years from the Russian Know Your Heart study (KYH) (n = 3833) and the seventh survey of the Norwegian Tromsø Study (n = 5598). Maximum grip strength (kg) was assessed using the same protocol and device in both studies. Grip strength by age, sex and study was modelled using linear regression and between‐study differences were predicted from these models. Sex‐specific age‐standardized differences in grip strength and in prevalence of low muscle strength were estimated using the European population standard of 2013. Results Normal ranges of maximum grip strength in both studies combined were 33.8 to 67.0 kg in men and 18.7 to 40.1 kg in women. Mean grip strength was higher among Tromsø than KYH study participants and this difference did not vary markedly by age or sex. Adjustment for covariates, most notably height, attenuated between‐study differences but these differences were still evident at younger ages. For example, estimated between‐study differences in mean grip strength in fully adjusted models were 2.2 kg [95% confidence interval (CI) 1.4, 3.1] at 40 years and 1.0 kg (95% CI 0.5, 1.5) at 65 years in men (age × study interaction P = 0.09) and 1.1 kg (95% CI 0.4, 1.9) at age 40 years and −0.2 kg (95% CI −0.7, 0.3) at 65 years in women (age × study interaction P < 0.01). Conclusions We found between‐study differences in mean grip strength that are likely to translate into greater future risk of sarcopenia and poorer prospects of healthy ageing for Russian than Norwegian study participants. For example, the average Russian participant had a similar level of grip strength to a Norwegian participant 7 years older. Our findings suggest these differences may have their origins in childhood highlighting the need to consider interventions in early life to prevent sarcopenia.

【 授权许可】

Unknown