2-(Fluoromethyl)-4,7-dimethoxy-1-methyl-1H-benzimidazole

Molbank

DennisA. Smith¹  Pau Farràs¹  Fawaz Aldabbagh¹  Patrick Kielty¹ 

[1] School of Chemistry, National University of Ireland Galway, University Road, H91 TK33 Galway, Ireland;

关键词: fluorine;    nitrogen heterocycles;    nitroxide;    radicals;    Selectfluor;    TEMPO;   

DOI  :  10.3390/M1129

来源: DOAJ

【 摘 要 】

Selectfluor (1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)) substitutes the TEMPO free radical with fluorine on 4,7-dimethoxy-1-methyl-2-{[(2,2,6,6-tetramethylpiperidin-1-yl)oxy]methyl}-1H-benzimidazole to give the title compound in a 77% yield. A mechanism is proposed for the formation of this novel methylene fluoride.

【 授权许可】

Unknown