Bone And Soft Tissue Changes In Patients With Spinal Cord Injury And Multiple Sclerosis

Folia Medica

Papathanasiou Jannis¹  Papagelopoulos Panayiotis²  Mavrogenis Andreas²  Dionyssiotis Yannis²  Skarantavos Grigorios²  Trovas Georgios³ 

[1] Department of Kinesiotherapy and Physiotherapy, Faculty of Public Health, Medical University, Sofia, Bulgaria;First Department of Orthopaedics, ATTIKON University Hospital, Athens University Medical School, Athens, Greece;Laboratory for Research of the Musculoskeletal System, KAT Hospital, Athens University Medical School, Athens, Greece;

关键词: spinal cord injury;    multiple sclerosis;    bone;    muscle and fat loss;    osteoporosis;    травмы позвонкового мозга;    множественный склероз;    кости;    мышечная и липидная (жировая) потеря;    остеопороз;   

DOI  :  10.1515/folmed-2015-0002

来源: DOAJ

【 摘 要 】

In patients with spinal cord injury and multiple sclerosis, deterioration of body composition (changes in bone, fat and muscle mass) is associated with increased risk for diseases such as coronary artery heart disease, non-insulin dependent diabetes mellitus, lipid metabolism abnormalities, and osteoporotic fractures in these patients. Immobility leads to a changing pattern of loading in the paralyzed areas, and secondary alteration in structure. However, bone and soft tissue changes in these patients are usually neglected. The purpose of this article is to update on the pathophysiological mechanisms leading to bone and soft tissue changes, and to increase the awareness of the treating physicians with respect to bone, muscle and fat loss and their consequences aiming to obtain measures to prevent bone and soft tissue loss in these patients.

【 授权许可】

Unknown