Prostatic signet-ring adenocarcinoma: A case report

Journal of Men's Health

Ali Al Khader¹  Esra Nsour²  Taleb Al Edwan³ 

[1] Department of Pathology and Forensic Medicine, Faculty of Medicine, Al-Balqa Applied University, 19117 Al-Salt, Jordan;Department of Pathology, Al Hussein Salt Hospital, Ministry of Health, 19117 Al-Salt, Jordan;Department of Urology, Al-Hussein Salt Hospital, Ministry of Health, 19117 Al-Salt, Jordan;

关键词: carcinoma;    prostate;    signet ring cell;   

DOI  :  10.31083/j.jomh1804090

来源: DOAJ

【 摘 要 】

Background: Prostatic signet-ring adenocarcinoma is a rare histological variant of prostate cancer. The tumor is characterized by an aggressive clinical course. Methods: Herein we present the case of a 78-year-old man with obstructive urinary symptoms and elevated serum prostate specific antigen. Transurethral resection of the prostate was performed. Results: Histologically, a tumor that was mainly composed of signet ring cells was identified. The tumor cells were positive for alcian blue special stain. Another Gleason 4 adenocarcinoma component was identified. The patient received hormonal therapy. A favorable response was documented at 8 months of follow up. Conclusions: Ruling out another primary site of origin, such as the gastrointestinal tract, is mandatory, and a more aggressive management plan should be put in mind.

【 授权许可】

Unknown