Prevalence of multi-drug resistant (MDR) and extensively drug-resistant (XDR) phenotypes of Pseudomonas aeruginosa and Acinetobacter baumannii isolated in clinical samples from Northeast of Iran

BMC Research Notes

Zahra Norouzi Bazgir¹  Hamid Reza Goli¹  Bahman Mirzaei¹  Fatemeh Iranpour²  Ryhaneh Babaei²  Fatemeh Mohammadi² 

[1] Department of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Science;Department of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Science;

关键词: Multi-drug resistant (MDR);    Extensively-drug resistant (XDR);    Pseudomonas aeruginosa;    Acinetobacter baumannii;    Carbapenem resistant A. baumannii;    Nosocomial infections;   

DOI  :  10.1186/s13104-020-05224-w

来源: DOAJ

【 摘 要 】

Abstract Objective Multi and extensively drug-resistant (MDR and XDR), Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) are two main causative agents of nosocomial infections leading to increased morbidity and mortality. We aim to study the prevalence of MDR and XDR-A. baumannii and P. aeruginosa phenotypes in clinical specimens. We conducted this for 1 year (2017–2018) and isolated bacteria from the clinical samples. Then, XDR and MDR strains were determined by susceptibility testing (disc diffusion). Results Out of 3248 clinical samples, A. baumannii and P. aeruginosa strains were detected in 309(9.51%) of them. Susceptibility testing indicated that (16.50%) and (15.53%) of the P. aeruginosa and (74.75%) and (73.13%) of the A. baumannii isolates were screened as the MDR and XDR strains. The frequency of MDR isolates was higher in wound samples 222 (71.8%). This rate in behavioral intensive care unit (BICU) and restoration ward, were 187 (60.5%) and 63 (20.4%). The frequency of XDR isolates in BICU 187 (59.54%), restoration 58(18.77%), and burns 30 (9.70%) were assessed as well. Considering high isolation rates of MDR and XDR of mentioned strains, it is necessary to apply prevention criteria for eradication of the mentioned bacteria from hospital wards.

【 授权许可】

Unknown