Botanical candidates from Saudi Arabian flora as potential therapeutics for Plasmodium infection

Saudi Journal of Biological Sciences

Mostafa A. Abdel-Maksoud¹  Esam M. Al-Shaebi²  Saleh Al-Quraishy²  Mohamed A. Dkhil² 

[1] Corresponding author.;Department of Zoology, College of Science, King Saud University, Saudi Arabia;

关键词: Chemotherapy;    Drug resistance;    Endemic disease;    Malaria;    Natural products;   

DOI  :  

来源: DOAJ

【 摘 要 】

Malaria is a lethal parasitic disease affecting over two hundred million people worldwide and kills almost half a million people per year. Until now, there is no curative treatment for this disease that has a substantial morbidity. The available chemotherapeutic agents are unable to completely control the infection with the continuous appearance of drug resistance. Consequently, the search for new therapeutic agents with high safety profiles and low side effects is of paramount importance. Several natural products have been investigated and proven to have antimalarial effects either in vivo or in vitro. A large number of plants have been studied globally for their antimalarial activities. However, studies that have been conducted in this field in Saudi Arabia are not enough. This article presents global and local research on the need for novel natural antimalarial agents with a particular emphasis on studies involving plants from Saudi Arabian flora.

【 授权许可】

Unknown