Recent Radiomics Advancements in Breast Cancer: Lessons and Pitfalls for the Next Future

Current Oncology

Barbara Alicja Jereczek-Fossa¹  Giorgio Maria Agazzi²  Filippo Pesapane³  Valeria Dominelli³  Enrico Cassano³  Silvia Penco³  Anna Rotili³  Francesca Botta⁴  Sara Raimondi⁵  Marta Cremonesi⁶  Gianpaolo Carrafiello⁷ 

[1] Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy;Department of Radiology, University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy;Division of Breast Radiology, IRCSS, IEO European Institute of Oncology, 20141 Milan, Italy;Medical Physics Unit, IRCSS, IEO European Institute of Oncology, 20141 Milan, Italy;Molecular and Pharmaco-Epidemiology Unit, Department of Experimental Oncology, IRCSS, IEO European Institute of Oncology, 20139 Milan, Italy;Radiation Research Unit, IRCSS, IEO European Institute of Oncology, 20141 Milan, Italy;Radiology Unit, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy;

关键词: radiomics;    breast cancer;    radiology;    oncology;    medical physics;    radiotherapy;   

DOI  :  10.3390/curroncol28040217

来源: DOAJ

【 摘 要 】

Radiomics is an emerging translational field of medicine based on the extraction of high-dimensional data from radiological images, with the purpose to reach reliable models to be applied into clinical practice for the purposes of diagnosis, prognosis and evaluation of disease response to treatment. We aim to provide the basic information on radiomics to radiologists and clinicians who are focused on breast cancer care, encouraging cooperation with scientists to mine data for a better application in clinical practice. We investigate the workflow and clinical application of radiomics in breast cancer care, as well as the outlook and challenges based on recent studies. Currently, radiomics has the potential ability to distinguish between benign and malignant breast lesions, to predict breast cancer’s molecular subtypes, the response to neoadjuvant chemotherapy and the lymph node metastases. Even though radiomics has been used in tumor diagnosis and prognosis, it is still in the research phase and some challenges need to be faced to obtain a clinical translation. In this review, we discuss the current limitations and promises of radiomics for improvement in further research.

【 授权许可】

Unknown