Control of Energy Transfer Between Pyrene‐ and Perylene‐Nucleosides by the Sequence of DNA‐Templated Supramolecular Assemblies

ChemistryOpen

Dr. Yannic Fritz¹  Sara Müller¹  Prof. Hans‐Achim Wagenknecht¹ 

[1] Institute of Organic Chemistry Karlsruhe Institute of Technology (KIT) Fritz-Haber-Weg 6 76131 Karlsruhe Germany;

关键词: oligonucleotides;    helicity;    circular dichroism;    fluorescence;    absorbance;   

DOI  :  10.1002/open.201900346

来源: DOAJ

【 摘 要 】

Abstract DNA was used as supramolecular scaffold to order chromophores and control their optical properties. Ethynylpyrene as energy donor was attached to 2′‐desoxy‐2‐aminoadenosine that binds selectively to thymidines (T) in the template. Ethynylperylene as acceptor was attached to 2′‐desoxyuridine that is complementary to 2′‐desoxyadenosine (A). This donor‐acceptor pair was assembled along single‐stranded DNA templates of different A−T sequences to investigate the sequence control of the energy transfer between the chromophores. The fluorescence intensities increase in the mixed assemblies along the DNA templates from A10T10 over (AATT)5 to (AT)10, although these templates provide equal numbers of potential binding sites for the two different nucleoside chromophore conjugates and exhibit similar absorbances. This shows that the sequence selective assembly of the two building blocks along DNA templates is programmable and alters the fluorescence readout. Such sequence‐controlled supramolecular chemistry represents the key element for future functional π‐systems in materials for light harvesting of solar energy.

【 授权许可】

Unknown