Different memory patterns of digits: a functional MRI study

Journal of Biomedical Science

Bin Liu¹  Jinlong Zheng²  Yongming Wu³  Zengqiang Zhang⁴  Sheng Tan⁴  Lin Ma⁵  Zhibo Wen⁶  Chunhua Zhu⁷  Sheng Wu⁷  Jianghua Xu⁸  Bin Wang⁹  Hong Li⁹  Siyun Shu⁹  Jingxin Nie^1,10  Xin Yang^1,11 

[1] Department of Emergency, Zhujiang Hospital, Southern Medical University;Department of Neurology, Huai’an First People’s Hospital, Nanjing Medical University;Department of Neurology, Nanfang Hospital, Southern Medical University;Department of Neurology, Zhujiang Hospital, Southern Medical University;Department of Radiology, The General Hospital of Chinese People’s Liberation Army;Department of Radiology, Zhujiang Hospital, Southern Medical University;Hangzhou Sanatorium of Army;Hangzhou Sanatorium of air force;Pediatric Center, Zhujiang Hospital, Southern Medical University;School of Psychology, Center for Studies of Psychological Application, South China Normal University;The first Sanatorium of PLA Navy;

关键词: Memory for numeric figures;    Short-term memory;    Long-term memory;    Working memory;    Striatum;   

DOI  :  10.1186/s12929-019-0516-y

来源: DOAJ

【 摘 要 】

Abstract Background Psychological investigations and functional imaging technology have been used to describe neural correlations of different types of memory with various stimuli. Memory with limited storage capacity and a short retention time can be classified as short-term memory (STM) while long-term memory (LTM) can be life-long without defined capacity. Methods To identify brain activation pattern associated with different modes of memory for numerical figures, we detected brain activities from twenty-two healthy subjects when performing three types of memory tasks for numbers, namely STM, LTM and working memory (WM), by using functional magnetic resonance imaging (fMRI) technique. Results The result revealed variable patterns of activation in different brain regions responding to different types of memory tasks. The activation regions with primary processing and transient maintenance of STM for numerical figures are located in the visual cortex and mainly encoded by visual representations, while LTM was encoded by semantics and mainly recruiting left frontal cortex. We also found that subcortical structures, such as the caudate nucleus and the marginal division of the striatum, plays important roles in working memory. Conclusions Activation of different brain regions in these three kinds of memories, indicating that different kinds of memories rely on different neural correlates and mental processes.

【 授权许可】

Unknown