Incidental Merkel cell carcinoma in a cutaneous horn: a case report.

Dermatology Practical & Conceptual

Tyler B. Rouse¹  Brian A. Schick²  Mariamma G. Joseph²  Manal Y. Gabril²  Joshua S. Tobe³ 

[1] Department of Pathology, Huron Perth Healthcare Alliance, Stratford General Hospital, Stratford, Ontario, Canada;Department of Pathology, London Health Sciences Centre and Western University, London, Ontario, Canada;Schulich School of Medicine & Dentistry and Western University, London, Ontario, Canada;

关键词: Merkel cell carcinoma;    squamous cell carcinoma;    cutaneous horn;   

DOI  :  10.5826/dpc.0501a08

来源: DOAJ

【 摘 要 】

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.

【 授权许可】

Unknown