HIV incidence and sexual behavioral correlates among 4578 men who have sex with men (MSM) in Chengdu, China: a retrospective cohort study

BMC Public Health

Jinghua Li¹  Yuantao Hao²  Wangnan Cao³  Joseph Tak-fai Lau⁴  Xiaodong Wang⁵  Jibin Li⁶  Phuong Mai Le⁷  Stuart Gilmour⁷  Huachun Zou⁸  Dannuo Wei⁹  Jing Gu⁹  Chun Hao⁹  Yang Deng⁹  Xinyi You⁹  Liping Peng⁹ 

[1] Collaborative Innovation Center for Cancer Medicine;State Key Laboratory of Oncology in South China;Center for Evidence Synthesis in Health, School of Public Health, Brown University;Centre for Health Behaviours Research, JC School of Public Health and Primary Care, The Chinese University of Hong Kong;Chengdu Tongle Health Consulting Service Center;Department of Clinical Research, Sun Yat-sen University Cancer Center;Graduate School of Public Health, St. Luke’s International University;School of Public Health (Shenzhen), Sun Yat-sen University;School of Public Health, Sun Yat-sen University (North Campus);

关键词: HIV/AIDS;    Incidence;    Men who have sex with men;    Cohort studies;    Sexual behavior;   

DOI  :  10.1186/s12889-021-10835-4

来源: DOAJ

【 摘 要 】

Abstract Background The prevalence of HIV among men who have sex with men (MSM) in southwest China is still increasing. This study aimed to investigate the trend in HIV incidence and its associated risk factors among MSM in Chengdu, China. Method Incidence data were collected from the largest local non-governmental organization (NGO) serving MSM in Chengdu between 2012 and 2018, while information on sexual behaviors was collected from 2014. All MSM who received voluntary counseling and testing services (VCT) in the collaborating NGO at least twice during the study period were included. We calculated the HIV incidence density among MSM every 2 years and the overall incidence rate. A Cox proportional hazards regression model was employed to identify risk factors for HIV infection. Result A total of 4578 HIV-negative participants were included in the cohort. The total incidence density was 5.95 (95% CI: 5.37–6.56)/100 person-years (PYs) between 2012 and 2018. The segmented incidence density was 9.02 (95% CI: 7.46–10.78), 5.85 (95% CI: 4.86–6.97), 5.43 (95% CI: 4.53–6.46), and 3.09 (95% CI: 2.07–4.41)/100 PYs in 2012–2013, 2014–2015, 2016–2017, and 2018, respectively. After adjusting for sociodemographic characteristics, compared to participants without sexual partners within 6 months, MSM with one fixed partner (Adjusted Hazard Ratio, AHR = 1.18, 95% CI: 0.44–3.19) and more than five partners (AHR = 2.24, 95% CI: 0.81–6.20) had increased risk of HIV infection. MSM who used condom inconsistently had a higher risk of HIV infection (AHR = 1.87, 95% CI: 1.46–2.38) compared to consistent condom users. Conclusion The decreased HIV incidence density among MSM was potentially related to the successful comprehensive HIV prevention strategies in Chengdu. Multiple male sexual partnerships and inconsistent condom use during anal intercourse were risk factors associated with HIV occurrence.

【 授权许可】

Unknown