Patch Testing with a New Composition of Mercapto Mix: A Multi­centre Study by the Swedish Contact Dermatitis Research Group

Acta Dermato-Venereologica

Malin Engfeldt¹  Mihály Matura²  Cecilia Svedman²  Bo Glas²  Anna Löfnertz Petersson²  Berndt Stenberg²  Marléne Isaksson²  Magnus Bruze²  Lina Hagvall² 

[1] Lund University, Department of Occupational and Environmental Dermatology, Clinical Sciences, SE-20502 Malmö, Sweden. ;;

关键词: allergic contact dermatitis;    contact allergy;    2-mercaptobenzothiazole;    mercapto mix;    rubber;    delayed hypersensitivity;   

DOI  :  10.2340/00015555-3249

来源: DOAJ

【 摘 要 】

This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch- tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0–0.50%, 0–0.93%, and 0–1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.

【 授权许可】

Unknown