The mechanism and treatment of blood-retinal barrier injury

Guoji Yanke Zazhi

Min Li¹  Quan-Peng Zhang¹  Shi-Wen Mo¹  Yi Li² 

[1]College of Basic Medicine and Life Sciences, Hainan Medical University, Haikou 571199, Hainan Province, China

[2]First Clinical College, Hainan Medical University,Haikou 571199, Hainan Province, China

关键词: blood-retinal barrier;    diabetic retinopathy;    acute glaucoma;    retinopathy of prematurity;    tight junction protein;    vascular endothelial growth factor;   

DOI  :  10.3980/j.issn.1672-5123.2020.11.13

来源: DOAJ

【 摘 要 】

The blood-retinal barrier(BRB)plays an important role in maintaining the homeostasis of the retinal microenvironment. Many diseases can lead to the damage of BRB, such as diabetic retinopathy, acute glaucoma and retinopathy of prematurity. At present, the molecular mechanism of BRB injury has not been fully explained. This paper briefly reviews the structure and function of blood-retina barrier, the damage mechanism of blood-retina barrier caused by various ocular diseases, and the therapeutic countermeasures of drug therapy, laser therapy and surgical treatment.

【 授权许可】

Unknown