Reduction in COVID-19 prevalence in healthcare workers in a university hospital in southern Brazil after the start of vaccination

International Journal of Infectious Diseases

Fernando Schmidt Fernandes¹  Anderson Yudi Takahasi²  Maria Carlota Borba Brum³  Sheila de Castro Cardoso Toniasso⁴  Robson Martins Pereira⁴  Dvora Joveleviths⁴  Luciana Pereira da Silva⁴  Fábio Fernandes Dantas Filho⁵  Camila Pereira Baldin⁶ 

[1] Corresponding author.;Head of the Occupational Medicine Service, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos, Porto Alegre, Rio Grande do Sul 2350, Brazil;Nurse, Occupational Medicine Service, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos, Porto Alegre, Rio Grande do Sul 2350, Brazil;Physician, Occupational Medicine Service, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos, Porto Alegre, Rio Grande do Sul 2350, Brazil;Professor of Medicine, Federal University of Rio Grande do Sul, Ramiro Barcelos, Porto Alegre, Rio Grande do Sul 2350, Brazil;Resident, Medical Residency Program in Occupational Medicine, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil;

关键词: COVID-19;    SARS-CoV-2;    healthcare workers;    vaccine;   

DOI  :  

来源: DOAJ

【 摘 要 】

Introduction: The quick spread of SARS-CoV-2 led to the development of vaccines that are capable of reducing infection and the number of more severe COVID-19 cases. Aim: To assess COVID-19 prevalence among healthcare workers (HCWs) after vaccination against SARS-CoV-2. Methods: This was a cross-sectional study on the prevalence of COVID-19 diagnosis among 7523 HCWs vaccinated against SARS-CoV-2 with CoronaVac and ChAdOx1 nCoV-19 in a university hospital, in southern Brazil, between January 18 and March 18, 2021.The variables evaluated were: sex, age, work area, role, source of infection, previous diagnosis of COVID-19, date of vaccine administration, type of vaccine, and need for hospitalization. The statistical analysis used Poisson regression and Fisher's exact test with SPSS software version 25, and a level of significance set at 5%. Results: 813 vaccinated HCWs showed symptoms suggestive of COVID-19, of whom 35.4% (288) had a detectable result after undergoing RT-PCR for SARS-CoV-2. There was a reduction of 62% in new cases of COVID-19 among HCWs in the institution 7 weeks after the start of vaccine rollout. Conclusion: Our data suggest that the vaccines used by the institution reduced the number of COVID-19 cases among healthcare workers, demonstrating the effectiveness of the vaccines.

【 授权许可】

Unknown