Prophylactic catheter ablation for ventricular tachycardia reduces morbidity and mortality in patients with implantable cardioverter–defibrillator devices

Journal of Arrhythmia

Jun Oikawa¹  Hidehira Fukaya¹  Shinichi Niwano¹ 

[1] Department of Cardio‐angiology, Kitasato University School of Medicine, Japan;

关键词: Ventricular tachycardia;    Ablation;    Implantable cardioverter–defibrillator;    Cardiac resynchronization therapy;    Prognosis;   

DOI  :  10.1016/j.joa.2013.05.003

来源: DOAJ

【 摘 要 】

Abstract Background Although the use of implantable cardioverter–defibrillator/cardiac resynchronization therapy device with a defibrillator (ICD/CRT‐D) is the principal therapy for patients with life‐threatening ventricular tachyarrhythmias/ventricular fibrillation (VT/VF), prophylactic VT ablation may reduce arrhythmic episodes and mortality in patients with an ICD/CRT‐D. In this retrospective study, the prognoses among patient groups with different results of attempted VT ablation were compared. Methods The study population consisted of 151 consecutive patients with an ICD/CRT‐D and structural heart disease. The mean age was 64±9 years, and 63 of the 151 patients were women. Of the 151 patients, 117 cases underwent catheter ablation procedure for elimination of monomorphic VT. The 151 patients were divided into 3 groups based on the results of the ablation or whether ablation was attempted, i.e., success, failure, and not‐attempted groups (n=87, 30, and 34, respectively). The event rate of VT/VF and total mortality were compared among the 3 groups. Results During a follow‐up period of 31±22 months, VT/VF episodes and death occurred in 45 (30%) and 16 (11%) patients, respectively. When comparing the 3 groups, the rates of VT/VF episodes and death were significantly lower in the success group than in the failure and not‐attempted groups (16.1%, 46.7%, 50.0%, p=0.0001 and 6.9%, 20.0%, 11.8%, p=0.0213, respectively). Conclusion In patients with an ICD/CRT‐D implant for VT/VF, prophylactic ablation of monomorphic VT may reduce morbidity and mortality.

【 授权许可】

Unknown