Dry eye disease immune responses and topical therapy

Eye and Vision

Charles W. McMonnies¹ 

[1] School of Optometry and Vision Science, University of New South Wales;

关键词: Dry eye disease;    Topical drugs;    Cyclosporine;   

DOI  :  10.1186/s40662-019-0137-2

来源: DOAJ

【 摘 要 】

Abstract There is accumulating evidence that inflammation is one of the key components of dry eye because chronic ocular surface inflammation can be both a result as well as an initiator of dry eye. The need for continuing anti-inflammatory therapy may be determined in part by the extent that non-modifiable factors such as gender and age-related aqueous or lipid or mucus production deficiencies contribute to its chronicity. This perspective examines how the need for increased dosage of a topical anti-inflammatory drug may be determined by the degree of difficulty that a topically administered drug has in accessing different sites of tear deficiency and associated inflammation.

【 授权许可】

Unknown