Epidemiological Characteristics and Transmissibility of Human Immunodeficiency Virus in Nanning City, China, 2001–2020

Frontiers in Public Health

Qun Li¹  Jing-An Cui²  Song-Bai Guo²  Qiuping Chen³  Roger Frutos³  Lina Zhou⁴  Liping Nong⁵  Shixiong Yang⁵  Jinglan Wu⁵  Mengni Nong⁵  Min Yao⁵  Na Luo⁵  Li Luo⁶  Bin Deng⁶  Meng Yang⁶  Weikang Liu⁶  Jiefeng Huang⁶  Tianlong Yang⁶  Jingwen Xu⁶  Yao Wang⁶  Peihua Li⁶  Yuanzhao Zhu⁶  Jia Rui⁶  Zhuoyang Li⁶  Xingchun Liu⁶  Tianmu Chen⁶  Shengnan Lin⁶  Chan Liu⁶  Qian Lin⁷  Chi Tang⁸  Shihai Chen⁸  Qingqing Hu⁹  Zeyu Zhao^1,10 

[1] 0Department of Health Emergency, Chinese Center for Disease Control and Prevention, Beijing, China;Department of Mathematics and Data Science, School of Science, Beijing University of Civil Engineering and Architecture, Beijing, China;Department of Medical Insurance Office, Xiang'an Hospital of Xiamen University, Xiamen, China;Department of Nephrology, The Second Hospital of Xiamen Medical College, Xiamen, China;Department of STD and AIDS Prevention and Treatment, Nanning Center for Disease Control and Prevention, Nanning, China;Department of Science and Technology, School of Public Health, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Xiamen University, Xiamen, China;Development Planning Office, Guangxi Medical University, Nanning, China;Division of Director's Office, Nanning Municipal Health Commission, Nanning, China;Division of Public Health, School of Medicine, University of Utah, 201 Presidents Circle, Salt Lake, UT, United States;Laboratory Intertryp CIRAD/IRD, Université de Montpellier, Montpellier, France;

关键词: human immunodeficiency virus;    transmission model;    transmissibility;    dynamics;    acquired immune deficiency syndrome;   

DOI  :  10.3389/fpubh.2021.689575

来源: DOAJ

【 摘 要 】

Background: Human immunodeficiency virus (HIV) is a single-stranded RNA virus that can weaken the body's cellular and humoral immunity and is a serious disease without specific drug management and vaccine. This study aimed to evaluate the epidemiologic characteristics and transmissibility of HIV.Methods: Data on HIV follow-up were collected in Nanning City, Guangxi Zhuang Autonomous, China. An HIV transmission dynamics model was built to simulate the transmission of HIV and estimate its transmissibility by comparing the effective reproduction number (Reff) at different stages: the rapid growth period from January 2001 to March 2005, slow growth period from April 2005 to April 2011, and the plateau from May 2011 to December 2019 of HIV in Nanning City.Results: High-risk areas of HIV prevalence in Nanning City were mainly concentrated in suburbs. Furthermore, high-risk groups were those of older age, with lower income, and lower education levels. The Reff in each stage (rapid growth, slow growth, and plateau) were 2.74, 1.62, and 1.15, respectively, which suggests the transmissibility of HIV in Nanning City has declined and prevention and control measures have achieved significant results.Conclusion: Over the past 20 years, the HIV incidence in Nanning has remained at a relatively high level, but its development trend has been curbed. Transmissibility was reduced from 2.74 to 1.15. Therefore, the prevention and treatment measures in Nanning City have achieved significant improvement.

【 授权许可】

Unknown