Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12)

مجله دانشگاه علوم پزشکی گرگان

Khodabakhshi B¹  Abbasi A²  Khosravian M³  Ghasemi Kebria F⁴  Hashemi Fard A⁵ 

[1] Associate Professor, Golestan Research Center of Gastroenterology and Hepatology-GRCGH, Department of Infectious Diseases, Golestan University of Medical Sciences, Gorgan, Iran;Associate Professor, Infectious Disease Research Center, Department of Infectious Diseases, Golestan University of Medical Sciences, Gorgan, Iran;General Physician, Golestan University of Medical Sciences, Gorgan, Iran;M.Sc in Microbiology, Golestan Research Center of Gastroenterology and Hepatology-GRCGH, Golestan University of Medical Sciences, Researcher, Young Researchers Club, Gorgan Branch, Islamic Azad University, Gorgan, Iran;Medical Student, Golestan University of Medical Sciences, Gorgan, Iran;

关键词: Tuberculosis;    Anti-TB drug;    Liver;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance. This study was carried out to determine the complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis. Methods: In this descriptive-analytic study, 1550 records of patients with TB in urban and rural health centers of Gorgan, north of Iran were assessed during 2007-12. Checklist consists of demographic and clinical data for each patient was recorded in a questionare. Results: 44 cases experienced the complications of anti-TB drugs. 27 (61.4%) of cases with complications were women. 77.3% and 22.7% of patients affected with pulmonary and extra pulmonary tuberculosis,respectively. 38.6% of patients were diabetic. The hepatic complication was seen in 37 cases (84.1%). Skin and other complications were seen in 5 and 2 cases, respectively. There was not any relationship between drug complications and other disases. Conclusion: Hepatic damage is the most common complication leading to hospitalization in tuberculosis patients using anti-TB drugs.

【 授权许可】

Unknown