Spondylodiscitis in Children: A Retrospective Study and Comparison With Non-vertebral Osteomyelitis

Frontiers in Pediatrics

Marco Roversi¹  Gianluca Mirra¹  Daniele Deriu¹  Antonio Musolino¹  Alberto Villani²  Domenico Barbuti³  Laura Lancella⁴  Andrzej Krzysztofiak⁴  Marco Crostelli⁵  Carlo Iorio⁵  Osvaldo Mazza⁵ 

[1] Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy;Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy;Department of Imaging, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy;Paediatric and Infectious Disease Unit, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy;Spine Surgery Unit, Department of Surgery and Transplantations, Bambino Gesù Children's Hospital, IRCSS, Rome, Italy;

关键词: spondylodiscitis;    osteomyelitis;    pediatrics;    children;    vertebra;    tuberculosis;   

DOI  :  10.3389/fped.2021.727031

来源: DOAJ

【 摘 要 】

Objectives: The aim of this study is to provide new data on pediatrics spondylodiscitis for an optimal clinical management of this site-specific osteomyelitis.Methods: We reported 48 cases of pediatric spondylodiscitis and made three comparisons between: (1) tubercular and non-tubercular cases; (2) patients aged more or less than 5 years; (3) children with spondylodiscitis and 62 controls with non-vertebral osteomyelitis.Results: A higher rate of sequelae was reported in patients with tubercular spondylodiscitis, but no significant differences were noted at the cut-off of 5 years of age. Compared to non-vertebral osteomyelitis, pediatric spondylodiscitis affects younger children of both genders, usually presenting with afebrile back pain, and requiring longer time to admission, hospitalization, and antibiotic therapy.Conclusion: Pediatric spondylodiscitis is an insidious disease with a non-specific presentation in childhood and peculiarities of its own. However, when clinical remission is obtained by an early start of broad-spectrum antibiotics, prolonging the therapy does not improve, nor worsens, the outcome. Surgical management is mandatory in case of vertebral instability and neurological signs but can be avoided when the infection is promptly treated with antibiotic therapy.

【 授权许可】

Unknown