Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales

Emerging Infectious Diseases

关键词: invasive pneumococcal disease;    pneumococcal conjugate vaccines;    serotype;    Streptococcus pneumoniae;    replacement disease;    capsular switching;   

DOI  :  10.3201/eid2410.180114

来源: DOAJ

【 摘 要 】

We observed a sudden and rapid increase in rare invasive pneumococcal disease serotype 7C, from an annual average of 3 cases during 2000–01 through 2015–16 to 29 cases in 2016–17. The increase was caused almost entirely by clonal expansion of sequence type 177, previously associated with vaccine serotype 19F.

【 授权许可】

Unknown