Phytosterols: Nutritional Health Players in the Management of Obesity and Its Related Disorders

Antioxidants

Teresa Vezza¹  Francisco Canet¹  Celia Bañuls¹  AranzazuM. de Marañón¹  Milagros Rocha¹  VíctorManuel Víctor¹ 

[1] Service of Endocrinology and Nutrition, University Hospital Doctor Peset, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), 46017 Valencia, Spain;

关键词: bioactive compounds;    phytosterols;    antioxidant properties;    anti-inflammatory properties;    microbiota;    obesity;   

DOI  :  10.3390/antiox9121266

来源: DOAJ

【 摘 要 】

Obesity and its related disorders, such as diabetes and cardiovascular risk, represent an emerging global health issue. Even though genetic factors seem to be the primary actors in the development and progression of these diseases, dietary choices also appear to be of crucial importance. A healthy diet combined with physical activity have been shown to ameliorate glycaemic levels and insulin sensitivity, reduce body weight and the risk of chronic diseases, and contribute to an overall improvement in quality of life. Among nutrients, phytosterols have become the focus of growing attention as novel functional foods in the management of metabolic disorders. Phytosterols are natural plant compounds belonging to the triterpene family and are structurally similar to cholesterol. They are known for their cholesterol-lowering effects, anti-inflammatory and antioxidant properties, and the benefits they offer to the immune system. The present review aims to provide an overview of these bioactive compounds and their therapeutic potential in the fields of obesity and metabolic disorders, with special attention given to oxidative stress, inflammatory status, and gut dysbiosis, all common features of the aforementioned diseases.

【 授权许可】

Unknown