New SiO2/Caffeic Acid Hybrid Materials: Synthesis, Spectroscopic Characterization, and Bioactivity

Materials

Michelina Catauro¹  Federico Barrino¹  Giuseppina Crescente²  Simona Piccolella²  Severina Pacifico²  Giovanni Dal Poggetto³ 

[1] Department of Engineering, University of Campania “Luigi Vanvitelli”, Via Roma 29, I-813031 Aversa, Italy;Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Via Vivaldi 43, 81100 Caserta, Italy;Ecoricerche, Srl, Via Principi Normanni, 81043 Capua (CE), Italy;

关键词: caffeic acid;    sol–gel technique;    ft-ir spectroscopy;    radical scavenging capacity;    antibacterial activity;   

DOI  :  10.3390/ma13020394

来源: DOAJ

【 摘 要 】

The sol−gel route represents a valuable technique to obtain functional materials, in which organic and inorganic members are closely connected. Herein, four hybrid materials, containing caffeic acid entrapped in a silica matrix at 5, 10, 15, and 20 wt.%, were synthesized and characterized through Fourier-Transform Infrared (FT-IR) and Ultraviolet-Visible (UV−Vis) spectroscopy. FT-IR analysis was also performed to evaluate the ability to induce the hydroxyapatite nucleation. Despite some structural changes occurring on the phenol molecular skeleton, hybrid materials showed scavenging properties vs. 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and 2,2′-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) radical cation (ABTS•⁺), which was dependent on the tested dose and on the caffeic acid wt.%. The SiO₂/caffeic acid materials are proposed as valuable antibacterial agents against Escherichia coli and Enterococcus faecalis.

【 授权许可】

Unknown