A Novel Efficient FEM Thin Shell Model for Bio-Impedance Analysis

Biosensors

Wuliang Yin¹  Jiawei Tang¹  Mingyang Lu¹  Yuedong Xie² 

[1] School of Electrical and Electronics Engineering, The University of Manchester, Manchester M13 9PL, UK;School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100036, China;

关键词: finite element method;    thin shell model;    ? dispersion;    Maxwell–Wagner effect;    bio-impedance spectroscopy;   

DOI  :  10.3390/bios10060069

来源: DOAJ

【 摘 要 】

In this paper, a novel method for accelerating eddy currents calculation on a cell model using the finite element method (FEM) is presented. Due to the tiny thickness of cell membrane, a full-mesh cell model requires a large number of mesh elements and hence intensive computation resources and long time. In this paper, an acceleration method is proposed to reduce the number of mesh elements and therefore reduce the computing time. It is based on the principle of replacing the thin cell membrane with an equivalent thicker structure. The method can reduce the number of mesh elements to 23% and the computational time to 17%, with an error of less than 1%. The method was verified using 2D and 3D finite element methods and can potentially be extended to other thin shell structures. The simulation results were validated by measurement and analytical results.

【 授权许可】

Unknown