Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin

Current Issues in Pharmacy and Medical Sciences

Borzecka Agnieszka¹  Jodlowska-Jedrych Barbara²  Wawryk-Gawda Ewelina²  Lis-Sochocka Marta²  Borzecki Pawel²  Chylinska-Wrzos Patrycja² 

[1] Chair and Department of Epidemiology and Clinical Research Methodology, Chodzki 1, 20-093Lublin, Poland;Chair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, Poland;

关键词: patulin;    mycotoxin;    interleukin 6;    mice;    liver;   

DOI  :  10.2478/cipms-2019-0008

来源: DOAJ

【 摘 要 】

Patulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test animals loaded with different doses of this mycotoxin. The research was conducted on mice which were assigned to 6 groups receiving different doses of active substances. After decapitation, their livers were taken for laboratory testing.

【 授权许可】

Unknown