Recent Progress on Molecular Photoacoustic Imaging with Carbon-Based Nanocomposites

Materials

Changho Lee¹  Su Woong Yoo¹  Ji Woo Kim²  Jieun Park²  Hyungwoo Kim²  Hea Ji Kim²  Songah Jeong² 

[1] Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, 264, Seoyang-ro, Hwasun-eup, Hwasun-gun 58128, Jeollanam-do, Korea;School of Polymer Science and Engineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Korea;

关键词: photoacoustic;    carbon materials;    molecular imaging;    contrast agents;    theragnosis;   

DOI  :  10.3390/ma14195643

来源: DOAJ

【 摘 要 】

For biomedical imaging, the interest in noninvasive imaging methods is ever increasing. Among many modalities, photoacoustic imaging (PAI), which is a combination of optical and ultrasound imaging techniques, has received attention because of its unique advantages such as high spatial resolution, deep penetration, and safety. Incorporation of exogenous imaging agents further amplifies the effective value of PAI, since they can deliver other specified functions in addition to imaging. For these agents, carbon-based materials can show a large specific surface area and interesting optoelectronic properties, which increase their effectiveness and have proved their potential in providing a theragnostic platform (diagnosis + therapy) that is essential for clinical use. In this review, we introduce the current state of the PAI modality, address recent progress on PAI imaging that takes advantage of carbon-based agents, and offer a future perspective on advanced PAI systems using carbon-based agents.

【 授权许可】

Unknown