Cerebral tuberculoma as a manifestation of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis

Journal of Neurosciences in Rural Practice

Abhijit Mandal¹  Arup Kumar Halder²  Anirban Das³  Sibes Kumar Das³ 

[1] BS Medical College, Bankura, India;Department of Respiratory Medicine, Columbia – Asia Hospital, Kolkata, West Bengal, India;Department of Respiratory Medicine, Medical College, Kolkata, India;

关键词: intracranial;    paradoxical reaction;    tuberculoma;    tuberculosis;   

DOI  :  10.4103/0976-3147.102622

来源: DOAJ

【 摘 要 】

Expansion of cerebral tuberculomas or their new appearance as a manifestation of paradoxical reaction in patients under antituberculous chemotherapy is well documented. Distinguishing paradoxical reaction from disease progression or treatment failure is an important issue in tuberculosis management. Five cases of cerebral tuberculomas are reported here as manifestations of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis on antituberculous treatment. Case 1 and 2 had tuberculous meningitis, Case 3 had miliary tuberculosis, Case 4 had miliary tuberculosis and destructive vertebral lesions, and Case 5 had pulmonary tuberculosis. Continuation of antituberculous drugs and addition of steroids led to full recovery of all patients.

【 授权许可】

Unknown