The Unrecognized Threat of Secondary Bacterial Infections with COVID-19

mBio

Mylene Vaillancourt¹  Peter Jorth¹ 

[1] Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA;

关键词: COVID-19;    SARS-CoV-2;    antibiotic resistance;    coinfection;    secondary bacterial infection;   

DOI  :  10.1128/mBio.01806-20

来源: DOAJ

【 摘 要 】

ABSTRACT Coronavirus disease 2019 (COVID-19) is the greatest pandemic of our generation, with 16 million people affected and 650,000 deaths worldwide so far. One of the risk factors associated with COVID-19 is secondary bacterial pneumonia. In recent studies on COVID-19 patients, secondary bacterial infections were significantly associated with worse outcomes and death despite antimicrobial therapies. In the past, the intensive use of antibiotics during the severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic led to increases in the prevalence of multidrug-resistant bacteria. The rising number of antibiotic-resistant bacteria and our decreasing capacity to eradicate them not only render us more vulnerable to bacterial infections but also weaken us during viral pandemics. The COVID-19 pandemic reminds us of the great health challenges we are facing, especially regarding antibiotic-resistant bacteria.

【 授权许可】

Unknown