Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives

Arabian Journal of Chemistry

关键词: Indole;    Pyridine;    Thiazolo[3,2-b][1,2,4]triazole;    Pyrazole;    Antioxidant;    Antimicrobial activity;   

DOI  :  10.1016/j.arabjc.2011.06.011

来源: DOAJ

【 摘 要 】

2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a–c) and its derivatives containing 1,2,4-triazole (4a–c), thiazolo[3,2-b][1,2,4]triazole (5a–c), hydrazide (6a–c), pyrazolones (7a–c) and (8a–c) were synthesized. Structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. The compounds were screened for their antioxidant and antimicrobial activities.

【 授权许可】

Unknown