期刊论文详细信息
Acta Chimica Slovenica
Synthesis and Biological Evaluation of Triazole linked Thiazolidenone Glycosides
Karthik Pulluri1  Srinivas Kontham1  Reddy Vasumathi1  Santhosh Madavarapu1  Sunitha Malladi1  Sri Nivas Avula2 
[1] ;Lec in chemistry;
关键词: Swern oxidation;    click reaction;    cyclisation;    antimicrobial;    nematicidal activity;   
DOI  :  10.17344/acsi.2016.2727
来源: DOAJ
【 摘 要 】

In a one pot procedure , a series of novel Triazole linked thiazolidenone derivatives  8 a-g and 9 a-g  was prepared by condensation of  (3aR,5S,6R,6aR)- 6-((1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyltetrahydro[2,3-d][1,3]dioxole-5- carbaldehyde  7 with mercapto acids and primary amines   in presence of ZnCl2  under both micro wave irradiation and conventional heating conditions. Compound  7 prepared  from di Acetone D- Glucose with oxidation followed by reduction , click reaction, primary acetonide deprotection and with oxidative cleavage .Characterization of new compounds has been done by means of IR, NMR, MS and elemental analysis. The nematicidal and anti bacterial activity of the compounds has also been evaluated.

【 授权许可】

Unknown   

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