MicroRNAs in Sarcopenia: A Systematic Review

Frontiers in Medicine

Kenichi Ishibashi¹  Akinori Aomatsu²  Shohei Kaneko³  Yoshiyuki Morishita³  Susumu Ookawara³  Katsunori Yanai³  Hiroki Ishii³  Kiyonori Ito³  Keiji Hirai³ 

[1] Department of Medical Physiology, Meiji Pharmaceutical University, Tokyo, Japan;Division of Intensive Care Unit, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan;Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan;

关键词: sarcopenia;    microRNA;    myotube;    myocyte;    myoblast;    systematic review;   

DOI  :  10.3389/fmed.2020.00180

来源: DOAJ

【 摘 要 】

Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.

【 授权许可】

Unknown