MicroRNAs in Sarcopenia: A Systematic Review

Frontiers in Medicine

article

Katsunori Yanai¹  Shohei Kaneko¹  Hiroki Ishii¹  Akinori Aomatsu²  Kiyonori Ito¹  Keiji Hirai¹  Susumu Ookawara¹  Kenichi Ishibashi³  Yoshiyuki Morishita¹ 

[1] Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University;Division of Intensive Care Unit, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University;Department of Medical Physiology, Meiji Pharmaceutical University

关键词: sarcopenia;    microRNA;    myotube;    myocyte;    myoblast;    systematic review;   

DOI  :  10.3389/fmed.2020.00180

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.

【 授权许可】

CC BY