Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Data in Brief

Martin Skott¹  Raluca G Maltesen²  Troels Ring²  Reinhard Wimmer³  Jørgen Frøkiær⁴  Søren Nielsen⁴  Munsoor A Hanifa⁵  Bodil S Rasmussen⁶ 

[1] Department of Anaesthesia and Intensive Care Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark;Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark;2A Pharma AB, Södergatan 3, 211 34 Malmö, Sweden;Department of Anaesthesia and Intensive Care Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark;Department of Chemistry and Bioscience, Aalborg University, 9220 Aalborg, Denmark;Department of Urology, Aarhus University Hospital, 8250 Aarhus N, Denmark;

关键词: Chronic kidney disease;    NMR;    Metabolomics;    Rat;    5/6 Nephrectomy;   

DOI  :  

来源: DOAJ

【 摘 要 】

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have been reported elsewhere (https://doi.org/10.1007/s11306-019-1569-3 [1]). The data could be useful to researchers working with human CKD or rat models of the disease. In addition, several different types of NMR spectra were recorded, including 1D NOESY, CPMG, and 2D J-resolved spectra, and the data could be useful for method comparison and algorithm development, both in terms of NMR spectroscopy and multivariate analysis.

【 授权许可】

Unknown