Stimuli-Directed Helical Chirality Inversion and Bio-Applications

Polymers

Kenan Shao¹  Ziyu Lv¹  Taolei Sun¹  Zhonghui Chen¹  Guangyan Qing¹ 

[1] State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, 122 Luoshi Road, Wuhan 430070, China;

关键词: helical chirality;    stimuli-responsive;    supramolecular assembly;    helical polymer;   

DOI  :  10.3390/polym8080310

来源: DOAJ

【 摘 要 】

Helical structure is a sophisticated ubiquitous motif found in nature, in artificial polymers, and in supramolecular assemblies from microscopic to macroscopic points of view. Significant progress has been made in the synthesis and structural elucidation of helical polymers, nevertheless, a new direction for helical polymeric materials, is how to design smart systems with controllable helical chirality, and further use them to develop chiral functional materials and promote their applications in biology, biochemistry, medicine, and nanotechnology fields. This review summarizes the recent progress in the development of high-performance systems with tunable helical chirality on receiving external stimuli and discusses advances in their applications as drug delivery vesicles, sensors, molecular switches, and liquid crystals. Challenges and opportunities in this emerging area are also presented in the conclusion.

【 授权许可】

Unknown