1,3-Dipolar Cycloaddition Reactions of 1-(4-Phenylphenacyl)-1,10-phenanthrolinium N-Ylide with Activated Alkynes

Molecules

Alkenes F. Dumitrascu¹  M. R. Caira²  C. Draghici¹  M. T. Caproiu¹ 

[1] Centre of Organic Chemistry "C. D. Nenitzescu", Romanian Academy, Spl. Independentei 202B, Bucharest 060023, Romania;Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

关键词: N-ylides;    1;    3-dipolar cycloaddition;    pyrrolophenanthrolines;    helical chirality;   

DOI  :  10.3390/10020321

来源: mdpi

【 摘 要 】

The 3+2 cycloaddition reaction of 1-(4-phenylphenacyl)-1,10-phenanthrolinium ylide 4 with activated alkynes gave pyrrolo[1,2-a][1,10]phenanthrolines 6a-d. The "one pot" synthesis of 6a,b,d from 4, activated alkenes, Et₃N and tetrakis-pyridine cobalt (II) dichromate (TPCD) is described. The helical chirality of pyrrolophenanthrolines 6b-d was put in evidence by NMR spectroscopy.

【 授权许可】

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