Conversion of Oximes to Carbonyl Compounds by Triscetylpyridinium Tetrakis(oxodiperoxotungsto) Phosphate (PCWP)-mediated Oxidation with Hydrogen Peroxide

Molecules

Francesco P. Ballistreri¹  Ugo Chiacchio²  Antonio Rescifina¹  Gaetano Tomaselli² 

[1] Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania 95125, Italy; E-mails

关键词: Oxidation of oximes;    oxodiperoxotungsto complex;    1;    3-dipolar cycloaddition;    nitrile oxides;    aldehydes.;   

DOI  :  10.3390/molecules13061230

来源: mdpi

【 摘 要 】

Aromatic and aliphatic oximes have been deoximated in chloroform-water to the corresponding aldehydes with dilute hydrogen peroxide and triscetylpyridinium tetrakis (oxodiperoxotungsto) phosphate as catalyst. The presence of dipolarophiles in the reaction mixtures allows a competitive reaction that converts oximes into isoxazole and isoxazoline derivatives via the intermediate formation of nitrile oxide species.

【 授权许可】

CC BY   
© 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.