Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)

Viruses

Hyuk-Chae Lee¹  Jun-Young Kim¹  Kyu-Jik Kim¹  Sol Jeong¹  Chang-Seon Song¹  Dam-Hee Park¹  Hyun-Jin Kim¹  Andrew Y. Cho¹  Jung-Hoon Kwon² 

[1] College of Veterinary Medicine, Konkuk University, 120, Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea;College of Veterinary Medicine, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea;

关键词: IBV;    avian coronavirus;    surveillance;    South Korea;    multiple introductions;    phylogenetic inference;   

DOI  :  10.3390/v13061045

来源: DOAJ

【 摘 要 】

Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 IBVs isolated in South Korea. Two IBV lineages, GI-15 and GI-19, were identified in South Korea. Phylogenetic analysis suggested that there were six distinct subgroups (KM91-like, K40/09-like, and QX-like I to IV) of the South Korean GI-19 IBVs. Among them, QX-type III and IV subgroups, which are phylogenetically different from those reported in South Korea in the past, accounted for more than half of the total. Moreover, the phylogeographic analysis of the QX-like subgroups indicated at least four distinct introductions of GI-19 IBVs into South Korea during 2001–2020. The efficacy of commercialized vaccines against the recently introduced QX-like subgroups should be verified, and continuous international surveillance efforts and quarantine procedures should be enhanced to prevent the incursion of viruses.

【 授权许可】

Unknown