Is ERAS effective and safe in laparoscopic gastrectomy for gastric carcinoma? A meta-analysis

World Journal of Surgical Oncology

Yu-long He¹  Ming-zhe Li¹  Liang Li¹  Heng-liang Zhu¹  Wen-hui Wu¹  Jian-feng Li¹  Xue-fu Zhou¹ 

[1] Department of Gastrointestinal Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University;

关键词: Fast-track surgery;    Gastric carcinoma;    Laparoscopic;    Meta-analysis;   

DOI  :  10.1186/s12957-018-1309-6

来源: DOAJ

【 摘 要 】

Abstract Background It is still unclear whether enhanced recovery after surgery is effective and safe in laparoscopic gastrectomy for gastric carcinoma. Methods Cochrane library databases, Medline, Embase, and Pubmed were searched from January 1, 1986, to December 31, 2016. Randomized controlled trials (RCTs) comparing fast-track recovery with conventional recovery strategies in laparoscopic radical gastrectomy for gastric carcinoma were included. The main outcomes measured were postoperative hospital stay, time to first flatus, hospital charge, and overall complication rate. Results Six RCTs with 400 patients were included in this study. Fast-track surgery has shorter postoperative hospital stays (weighted mean difference (WMD) − 2.65; 95% CI, − 4.01 to − 1.29, z = 3.82, P < 0.01) and less hospitalization expenditure (WMD − 523.43; 95% CI, − 799.79 to − 247.06, z = 3.71, P < 0.01) than conventional recovery strategies. There was no significant difference with respect to duration to first flatus (WMD − 17.72; 95% CI, − 39.46–4.02, z = 1.60, P = 0.11) and complication rate (OR 1.57; 95% CI, 0.82–2.98, z = 1.37, P = 0.17). Conclusions Enhanced recovery after surgery is effective and safe and is thus recommended in laparoscopic radical gastrectomy for gastric carcinoma.

【 授权许可】

Unknown