Caffeine citrate – Is it a silver bullet in neonatology?

Pediatrics and Neonatology

Gaurav Jawa¹  Bikash Shrestha² 

[1] Department of Neonatology, Fortis La Femme Hospital, New Delhi, India;Department of Paediatrics, Nepalese Army Institute of Health Sciences, Bhandarkhal, Sanobharyang, Kathmandu, Nepal;

关键词: caffeine;    apnea;    preterm;    ventilation;    extubation;   

DOI  :  10.1016/j.pedneo.2016.10.003

来源: DOAJ

【 摘 要 】

Caffeine citrate is one of the most prescribed drug in the present day NICU for apnea. Its efficacy, tolerability, wide therapeutic index and safety margin has made it the drug of choice among the methylxanthines. Its therapeutic uses in apnea of prematurity, mechanical ventilation, bronchopulmonary dysplasia has made it a “silver bullet” in neonatology. However, there are still controversies surrounding this drug. This review is aimed to update the reader about the basic pharmacology, current therapeutic uses, adverse effects, controversies as well as present and future research of caffeine.

【 授权许可】

Unknown