Single-parameter mechanical design of a 3D-printed octet truss topological scaffold to match natural cancellous bones

Materials & Design

Qiang Chen¹  Zhiyong Li²  Luping Wang³  Prasad K.D.V. Yarlagadda³  Qiwei Li⁴  Feipeng Zhu⁵ 

[1] School of Mechanical, Medical and Process Engineering, Queensland University of Technology, Brisbane QLD 4000, Australia;Bio-inspired Materials and Devices Laboratory, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China;Biomechanics Laboratory, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China;College of Mechanics and Materials, Hohai University, Nanjing 211100, China;School of Mechanical, Medical and Process Engineering, Queensland University of Technology, Brisbane QLD 4000, Australia;

关键词: 3D-printing;    Young’s modulus;    Strength;    Cellular solid;    Structure design;    Mathematical model;   

DOI  :  

来源: DOAJ

【 摘 要 】

Designing a suitable scaffold matching the mechanical properties of natural bones to optimize the bone regeneration is required in bone tissue engineering. The present work developed a single-parameter design method for the octet truss topological scaffold to achieve the accurate prediction and flexible adjustment of its Young’s modulus and strength. A theoretical model that formulated the normalized Young’s modulus and normalized yield strength of the octet truss scaffold by the single parameter (d/Ø) was proposed and further validated by uniaxial compression tests and FEA simulations. On the basis of the proposed model, the Young's modulus and yield strength of the octet truss scaffold made of different polymers with different d/Ø were mapped, and the ranges of suitable d/Ø that match the different natural cancellous bones were suggested. The results showed that the design method could accurately predict the porosity, specific area, normalized Young’s modulus and normalized yield strength, and adjust the mechanical properties of the scaffold in a wide range. The present work can be used for the design of scaffolds and the selection of constituent materials to obtain a suitable scaffold with desired mechanical properties, and has application prospects in the fields of bone tissue engineering and regenerative medicine.

【 授权许可】

Unknown