BMC Genomics | |
CBS: an open platform that integrates predictive methods and epigenetics information to characterize conserved regulatory features in multiple |
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关键词: Gene regulation; Genomics; Epigenomics; Comparative genomics; ChIP-seq; | |
DOI : 10.1186/1471-2164-13-688 | |
来源: DOAJ |
【 摘 要 】
Abstract
Background
Information about the composition of regulatory regions is of great value for designing experiments to functionally characterize gene expression. The multiplicity of available applications to predict transcription factor binding sites in a particular locus contrasts with the substantial computational expertise that is demanded to manipulate them, which may constitute a potential barrier for the experimental community.
Results
CBS (Conserved regulatory Binding Sites,
Conclusions
The CBS platform is a powerful resource that provides tools for data mining individual sequences and groups of co-expressed genes with epigenomics information to conduct regulatory screenings in
【 授权许可】
Unknown