Gastrointestinal stromal tumor of rectum- a case report

Global Journal of Medicine and Public Health

关键词: c-Kit;    Gastrointestinal stromal tumor;    Imatinib;    Rectal GIST;   

DOI  :  

来源: DOAJ

【 摘 要 】

Gastrointestinal stromal tumor (GIST) is an uncommon neoplasm of GI tract with rectum being rare site. Biopsy of the lesion and immunohistochemistry (IHC) confirms the diagnosis. Complete surgical resection is the principal curative procedure. Chemotherapy with Imatinib alone show cure in intermediate risk rectal GIST. We describe a case of a 45-year-old male with per rectal bleeding and generalized weakness. CT scan revealed rectal mass with metastasis in the right lobe of the liver. Rectal biopsy revealed intermediate grade tumor GIST which was confirmed on IHC (CD117 and CD34). Imatinib chemotherapy alone had good symptomatic improvement at 4 months of follow up.

【 授权许可】

Unknown