Assessment of amination reactions via nucleophilic aromatic substitution using conventional and eco-friendly energies

Green Chemistry Letters and Reviews

Fernando Ortega-Jiménez¹  Jessica V. González-Carrillo¹  Ricardo A. Luna-Mora¹  Francisco Barrera-Téllez¹  Hulme Ríos-Guerra¹  José G. Penieres-Carrillo¹  Ángeles Torres-Reyes¹  Oscar A. González-Cruz¹  Javier Perez-Flores² 

[1] Facultad de Estudios Superiores Cuautitlán-Universidad Nacional Autónoma de México;Universidad Nacional Autónoma de México, Ciudad Universitaria;

关键词: SNAr reactions;    amino(acetamido)-halo-nitro aromatic compounds;    assessment;    thermal energy;    alternative energy sources;   

DOI  :  10.1080/17518253.2018.1510992

来源: DOAJ

【 摘 要 】

The efficiency of conventional heating energy source compared with Infrared (IR), Ultrasound (US), Microwave and the simultaneous combination US–IR eco-friendly approaches for preparation of new N-(5-R1 -amino-2-nitrophenyl)acetamides and 5-R1-amino-2-nitroaniline by Nucleophilic Aromatic Substitution (SNAr) via addition–elimination reactions on the halogens F, Cl, Br, I, employing amines as nucleophiles were explored. Moreover, phenyldiazenyl derivatives in good yields by an oxidative one-pot SNAr-based amination reaction from an unusual oxidation of 2-phenylhydrazinyl derivatives in DMSO was prepared.

【 授权许可】

Unknown