Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes

Molecules

Bihui Zhou¹  Limei Fan¹  Linlin Li¹  Pu Chen¹  Wenzhe Ren¹  Dong Zou¹  Qiannan Luo¹  Jie Li¹  Fan Yang¹ 

[1] Department of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, China;

关键词: metal-free;    diarylmethane;    oxidation;    ketone;   

DOI  :  10.3390/molecules23081922

来源: DOAJ

【 摘 要 】

An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O2 as an oxidant and is promoted by commercially available MN(SiMe3)2 [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates.

【 授权许可】

Unknown