Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits

International Journal of Molecular Sciences

AndrésR. Schwember¹  AdrianoCosta de Camargo¹  Fereidoon Shahidi²  Emilio Alvarez-Parrilla³  LauraA. de la Rosa³  MaressaCaldeira Morzelle⁴  MárioRoberto Maróstica Júnior⁵  MarinaVilar Geraldi⁵  Marcelo Franchin⁶  BrunoTrevenzoli Favero⁷ 

[1] Departamento de Ciencias Vegetales, Facultad de Agronomía e Ingeniería Forestal, Pontificia Universidad Católica de Chile, Casilla 306-22, Santiago, Chile;Department of Biochemistry, Memorial University of Newfoundland, St. John’s, NL A1B 3X9, Canada;Department of Chemical Biological Sciences, Universidad Autónoma de Ciudad Juárez, Anillo Envolvente del Pronaf y Estocolmo, s/n, Cd, Juárez, Chihuahua 32310, México;Department of Food and Nutrition, Faculty of Nutrition, Federal University of Mato Grosso, Fernando Correa Avenue, P.O. box 2367, Cuiabá, MT 78060-900, Brazil;Department of Food and Nutrition, University of Campinas—UNICAMP, Campinas, SP 13083-862, Brazil;Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP 13414-903, Brazil;University of Copenhagen, Department of Plant and Environmental Sciences, 2630 Taastrup, Denmark;

关键词: legume seeds;    genetics;    phenolic antioxidants;    inflammation;    cardiovascular disease;    cancer;    diabetes;    obesity;   

DOI  :  10.3390/ijms20112644

来源: DOAJ

【 摘 要 】

Legume seeds are rich sources of protein, fiber, and minerals. In addition, their phenolic compounds as secondary metabolites render health benefits beyond basic nutrition. Lowering apolipoprotein B secretion from HepG2 cells and decreasing the level of low-density lipoprotein (LDL)-cholesterol oxidation are mechanisms related to the prevention of cardiovascular diseases (CVD). Likewise, low-level chronic inflammation and related disorders of the immune system are clinical predictors of cardiovascular pathology. Furthermore, DNA-damage signaling and repair are crucial pathways to the etiology of human cancers. Along CVD and cancer, the prevalence of obesity and diabetes is constantly increasing. Screening the ability of polyphenols in inactivating digestive enzymes is a good option in pre-clinical studies. In addition, in vivo studies support the role of polyphenols in the prevention and/or management of diabetes and obesity. Soybean, a well-recognized source of phenolic isoflavones, exerts health benefits by decreasing oxidative stress and inflammation related to the above-mentioned chronic ailments. Similar to soybeans, chickpeas are good sources of nutrients and phenolic compounds, especially isoflavones. This review summarizes the potential of chickpea as a substitute for soybean in terms of health beneficial outcomes. Therefore, this contribution may guide the industry in manufacturing functional foods and/or ingredients by using an undervalued feedstock.

【 授权许可】

Unknown