Antimicrobial susceptibility to β-lactam antibiotics and production of BRO β-lactamase in clinical isolates of Moraxella catarrhalis from a Japanese hospital

Journal of Microbiology, Immunology and Infection

Katsumi Arai¹  Kageto Yamada¹  Ryoichi Saito² 

[1] Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital, Tokyo, Japan;Department of Microbiology and Immunology, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Tokyo, Japan;

关键词: antimicrobial susceptibility;    β-lactam;    BRO β-lactamase;    ceftriaxone;    Moraxella catarrhalis;   

DOI  :  10.1016/j.jmii.2016.08.003

来源: DOAJ

【 摘 要 】

We investigated BRO-β-lactamase production of Moraxella catarrhalis isolates and its antimicrobial susceptibility to β-lactams. Of the 233 isolates, 232 were BRO producers and 224 were BRO-1 producers. Four isolates exhibited elevated ceftriaxone minimum inhibitory concentration (2 μg/mL) and different pulsed-field gel electrophoresis patterns and we expect this number to increase in the near future.

【 授权许可】

Unknown