Recent Advances on Quinazoline Derivatives: A Potential Bioactive Scaffold in Medicinal Chemistry

ChemEngineering

Mukty Sinha¹  Pooja Agarwal²  Ram Karan²  Neelima Mahato³ 

[1] Department of Medical Devices, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palej, Gandhinagar 382355, India;Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Yamuna Expressway, Greater Noida 203201, India;School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Korea;

关键词: quinazoline;    antifungal;    anticancer;    anti-inflammatory;    antibacterial;    antioxidant;   

DOI  :  10.3390/chemengineering5040073

来源: DOAJ

【 摘 要 】

This paper intended to explore and discover recent therapeutic agents in the area of medicinal chemistry for the treatment of various diseases. Heterocyclic compounds represent an important group of biologically active compounds. In the last few years, heterocyclic compounds having quinazoline moiety have drawn immense attention owing to their significant biological activities. A diverse range of molecules having quinazoline moiety are reported to show a broad range of medicinal activities like antifungal, antiviral, antidiabetic, anticancer, anti-inflammatory, antibacterial, antioxidant and other activities. This study accelerates the designing process to generate a greater number of biologically active candidates.

【 授权许可】

Unknown