Cancer Survival in Adults in Spain: A Population-Based Study of the Spanish Network of Cancer Registries (REDECAN)

Cancers

Paula Franch¹  Arantza López de Munain²  Visitación de Castro²  Amaia Molinuevo³  Araceli Alemán⁴  Dolores Rojas⁴  Ana Vizcaíno Batllés⁵  Matilde Chico⁶  Maria-José Sánchez⁷  Diego Salmerón⁷  María-Dolores Chirlaque⁷  Rafael Marcos-Gragera⁷  Rosario Jiménez Chillarón⁸  Enrique Ramalle-Gómara⁹  Marcela Guevara^1,10  Eva Ardanaz^1,10  Marta Rodríguez Camblor^1,11  Jaume Galceran^1,12  Marià Carulla^1,12 

[1] Balearic Islands Health Research Institute (IdISBa), Illes Balears, 07120 Palma, Spain;Basque Country Cancer Registry, Health Department, 01010 Vitoria, Spain;Biodonostia Health Research Institute, 20014 San Sebastian, Spain;Canary Islands Cancer Registry, Public Health Directorate, Canary Health Service, 35003 Las Palmas de Gran Canaria, Spain;Castellón Cancer Registry, Public Health Directorate, General Health Department, Generalitat Valenciana, 46020 Valencia, Spain;Ciudad Real Cancer Registry, Health and Social Welfare Authority, Castile-La Mancha, 13071 Ciudad Real, Spain;Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain;Cuenca Cancer Registry, Health and Social Welfare Authority, Castile-La Mancha, 16071 Cuenca, Spain;Department of Epidemiology and Prevention, La Rioja Regional Health Authority, 26071 Logroño, Spain;Navarra Public Health Institute, 31003 Pamplona, Spain;Public Health Directorate of Asturias, 33006 Oviedo, Spain;Tarragona Cancer Registry, Cancer Epidemiology and Prevention Service, Hospital Universitari Sant Joan de Reus, CatSalut, 43204 Reus, Spain;

关键词: cancer;    survival;    prognosis;    epidemiology;    population-based study;    cancer registries;   

DOI  :  10.3390/cancers14102441

来源: DOAJ

【 摘 要 】

The assessment of cancer survival at the population level is essential for monitoring progress in cancer control. We aimed to assess cancer survival and its trends in adults in Spain. Individual records of 601,250 adults with primary cancer diagnosed during 2002–2013 and followed up to 2015 were included from 13 population-based cancer registries. We estimated net survival up to five years after diagnosis and analyzed absolute changes between 2002–2007 and 2008–2013. Estimates were age-standardized. Analyses were performed for 29 cancer groups, by age and sex. Overall, age-standardized five-year net survival was higher in women (61.7%, 95% CI 61.4–62.1%) than in men (55.3%, 95% CI 55.0–55.6%), and ranged by cancer from 7.2% (pancreas) to 89.6% (prostate) in men, and from 10.0% (pancreas) to 93.1% (thyroid) in women in the last period. Survival declined with age, showing different patterns by cancer. Between both periods, age-standardized five-year net survival increased overall by 3.3% (95% CI 3.0–3.7%) in men and 2.5% (95% CI 2.0–3.0%) in women, and for most cancer groups. Improvements were greater in patients younger than 75 years than in older patients. Chronic myeloid leukemia and myeloma showed the largest increases. Among the most common malignancies, the greatest absolute increases in survival were observed for colon (5.0%, 95% CI 4.0–6.0%) and rectal cancers (4.5%, 95% CI 3.2–5.9%). Survival improved even for some cancers with poor prognosis (pancreas, esophagus, lung, liver, and brain cancer). Further investigation of possible sociodemographic inequalities is warranted. This study contributes to the evaluation of cancer control and health services’ effectiveness.

【 授权许可】

Unknown